Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579244 | 1.00 | ERN1 (0.55) | ERN1MAPTHTTKDM4EPOLB | |
| SCHEMBL9358680 | 0.81 | ERN1 (0.59) | ERN1MAPTHTTKDM4EPOLB | |
| SCHEMBL9358684 | 0.81 | ERN1 (0.59) | ERN1MAPTHTTKDM4EPOLB | |
| SCHEMBL29096543 | 0.81 | ERN1 (0.59) | ERN1MAPTHTTKDM4EPOLB | |
| SCHEMBL29096540 | 0.81 | ERN1 (0.59) | ERN1MAPTHTTKDM4EPOLB | |
| SCHEMBL17980514 | 0.78 | MAPT (0.40) | MAPTHTTKDM4EALDH1A1GAA | |
| SCHEMBL275826 | 0.78 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7820823 | 0.78 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL275825 | 0.78 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14198017 | 0.77 | ERN1 (0.67) | ERN1MAPTHTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |