Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18058919 | 0.88 | THRB (0.41) | TSHRMAOAHRH3THRBALDH1A1 | |
| SCHEMBL279033 | 0.87 | ALDH1A1 (0.52) | TSHRTHRBALDH1A1ESR1CHRM1 | |
| SCHEMBL278601 | 0.86 | TSHR (0.56) | TSHRCYP2D6MAOAHTR3AHRH3 | |
| SCHEMBL12380041 | 0.85 | ALDH1A1 (0.49) | TSHRCYP2D6MAOAHTR3AHRH3 | |
| SCHEMBL4645538 | 0.83 | TSHR (0.57) | TSHRCYP2D6THRBALDH1A1ESR1 | |
| SCHEMBL5579284 | 0.83 | EGFR (0.40) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL278718 | 0.80 | PHLPP2 (0.48) | TSHRCYP2D6MAOAHTR3AHRH3 | |
| SCHEMBL19141217 | 0.80 | TSHR (0.45) | TSHRCYP2D6MAOAHTR3AHRH3 | |
| SCHEMBL13567306 | 0.79 | THRB (0.49) | TSHRTHRBALDH1A1ESR1CHRM1 | |
| SCHEMBL13210553 | 0.79 | CA1 (0.59) | MAOAALDH1A1ESR1TDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052288-A1 | POLYMERISABLE PHOTOINITIATORS FOR LED CURABLE COMPOSITIONS | AGFA-GEVAERT (BE) | 2012-04-26 | — | — | WO | disclosed |