Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 19/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14905764 | 0.73 | PDE3B (0.39) | HCAR1PDE3BPDE3A | |
| SCHEMBL18237507 | 0.69 | PDE9A (0.36) | HCAR1PDE3BPDE3A | |
| SCHEMBL2643791 | 0.68 | HCAR1 (0.48) | HCAR1 | |
| SCHEMBL28936229 | 0.65 | HSD17B10 (0.59) | HCAR1 | |
| SCHEMBL1720850 | 0.63 | PDE3B (0.38) | HCAR1PDE3BPDE3A | |
| SCHEMBL29520927 | 0.61 | RECQL (0.43) | — | |
| SCHEMBL29828263 | 0.59 | MAPK8 (0.36) | HCAR1PDE3BPDE3A | |
| SCHEMBL30911404 | 0.58 | CYP19A1 (0.34) | — | |
| SCHEMBL30549011 | 0.58 | HPGD (0.40) | PDE3BPDE3A | |
| SCHEMBL30039796 | 0.58 | HPGD (0.40) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |