Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464450 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Ayapin SCHEMBL30171405 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Ayapin SCHEMBL6694210 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL6843275 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL28994323 | 0.70 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL3277376 | 0.68 | GAA (0.49) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL24788182 | 0.68 | CA9 (0.47) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL5579339 | 0.68 | GAA (0.46) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Xanthyletin SCHEMBL2120500 | 0.67 | CA12 (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL4740620 | 0.67 | GAA (0.48) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |