Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303231 | 0.74 | GAA (0.47) | GAAACHENPC1MGAMSI | |
| SCHEMBL3277376 | 0.70 | GAA (0.49) | GAAACHENPC1MGAMSI | |
| SCHEMBL28994323 | 0.69 | ALDH1A1 (0.59) | GAAACHENPC1MGAMSI | |
| SCHEMBL4740620 | 0.69 | GAA (0.48) | GAAACHENPC1MGAMSI | |
| Ayapin SCHEMBL6694210 | 0.68 | KDM4E (0.57) | GAAACHENPC1MGAMSI | |
| Ayapin SCHEMBL30171405 | 0.68 | KDM4E (0.57) | GAAACHENPC1MGAMSI | |
| SCHEMBL6843275 | 0.68 | KDM4E (0.57) | GAAACHENPC1MGAMSI | |
| SCHEMBL5579338 | 0.68 | KDM4E (0.50) | GAAACHENPC1MGAMSI | |
| SCHEMBL31708310 | 0.68 | GAA (0.47) | GAAACHENPC1MGAMSI | |
| SCHEMBL23302557 | 0.66 | GAA (0.61) | GAAACHENPC1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |