Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880116 | 0.81 | — | — | |
| SCHEMBL3060475 | 0.64 | ACVRL1 (0.34) | NPC1RAB9AJAK2MEN1KMT2A | |
| SCHEMBL10778839 | 0.63 | SMN1; SMN2 (0.52) | NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2360762 | 0.62 | GAA (0.34) | — | |
| SCHEMBL7004442 | 0.61 | PARP1 (0.42) | NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11405284 | 0.61 | SMN1; SMN2 (0.50) | NPC1RAB9AKMT2A | |
| SCHEMBL1182175 | 0.61 | NPC1 (0.31) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| Hydrochloric Acid SCHEMBL7001774 | 0.61 | PARP1 (0.45) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4686246 | 0.60 | HSP90AA1 (0.53) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1548213 | 0.60 | ALDH1A1 (0.69) | ROCK2ROCK1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | claimed |
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | HDAC5, HDAC4, HDAC3 | ROCK2 3822/4885ROCK1 3985/4885NPC1 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.