Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27123348 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL18766568 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL17849862 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL17849874 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL12110927 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL20812349 | 0.76 | CRBN (0.57) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL20812624 | 0.76 | CRBN (0.57) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL19359470 | 0.74 | CRBN (0.56) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL12108615 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4ECRBNKMT2ATDP1 | |
| SCHEMBL12108590 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4ECRBNKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |