Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.81 |
| ▸ | THRB | P10828 | 8/20 | 0.81 |
| ▸ | BLM | P54132 | 7/20 | 0.81 |
| ▸ | RECQL | P46063 | 6/20 | 0.81 |
| ▸ | TOP2A | P11388 | 5/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.81 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 4/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.81 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.81 |
| ▸ | FYN | P06241 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27869989 | 0.99 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL27907464 | 0.97 | MEN1 (0.78) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL7599040 | 0.96 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL18738448 | 0.96 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL28294533 | 0.95 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9028767 | 0.95 | MEN1 (0.79) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL43830 | 0.94 | MEN1 (0.83) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL19962290 | 0.94 | MEN1 (0.88) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL8535504 | 0.94 | EBP (0.77) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL14817634 | 0.94 | EBP (0.73) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340909-A | Preparation method and application of copper-doped ZIF-8 nanocomposite | 昆明理工大学 | 2024-07-16 | — | — | CN | claimed |
| CN-112237636-B | Method for synthesizing zwitterionic amphiphilic dendritic macromolecule and encapsulating anti-cancer drug by using amphiphilic dendritic macromolecule | 燕山大学 | 2022-05-24 | — | — | CN | claimed |
| CN-111888460-B | Preparation method of nano drug-loaded micelle with daptomycin-entrapped small-molecule hydrophobic drug | 燕山大学 | 2021-08-27 | — | — | CN | claimed |
| CN-112237636-A | Method for synthesizing zwitterionic amphiphilic dendritic macromolecule and coating anticancer drug by using amphiphilic dendritic macromolecule | 燕山大学 | 2021-01-19 | — | — | CN | claimed |
| CN-111888460-A | Preparation method of nano drug-loaded micelle with daptomycin-entrapped small-molecule hydrophobic drug | 燕山大学 | 2020-11-06 | — | — | CN | claimed |
| CN-104623685-B | A kind of mesenchyma stroma of tumors pH responsive types targeting dendrimers and preparation method thereof | 中国药科大学 | 2018-03-09 | — | — | CN | claimed |
| CN-118340909-A | Preparation method and application of copper-doped ZIF-8 nanocomposite | 昆明理工大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-114606190-A | Nano reagent for killing and foaming cells, cell micro-vesicle and preparation method and application thereof | 东南大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-112237636-B | Method for synthesizing zwitterionic amphiphilic dendritic macromolecule and encapsulating anti-cancer drug by using amphiphilic dendritic macromolecule | 燕山大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113616602-B | Recombinant high-density lipoprotein-polyamide-amine nano-composite, preparation method and application | 中国药科大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-113616602-A | Recombinant high-density lipoprotein-polyamide-amine nano-composite, preparation method and application | 中国药科大学 | 2021-11-09 | — | — | CN | disclosed |
| CN-111888460-B | Preparation method of nano drug-loaded micelle with daptomycin-entrapped small-molecule hydrophobic drug | 燕山大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-110037989-B | Self-cracking multifunctional liposome and application thereof | 东南大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-106265510-B | The multistage target polymer micella and preparation method thereof of pH trigger-type drug release in a kind of tumour cell | 宁夏医科大学 | 2019-11-05 | — | — | CN | disclosed |
| CN-110051857-A | A kind of preparation method and applications of the degradable mesoporous silica nano-particle of bimetal-doped multi-panel | 华侨大学 | 2019-07-26 | — | — | CN | disclosed |
| CN-109364253-A | One kind is for improving infiltrative nanoparticle of tumor tissues and its preparation method and application | 南开大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-108096214-A | A kind of magnetotactic bacteria quantum dot microcapsules and preparation method thereof | 曲阜师范大学 | 2018-06-01 | — | — | CN | disclosed |
| CN-104623685-B | A kind of mesenchyma stroma of tumors pH responsive types targeting dendrimers and preparation method thereof | 中国药科大学 | 2018-03-09 | — | — | CN | disclosed |
| US-20070275911-A1 | Targeted Drug-Formaldehyde Conjugates and Methods of Making and Using the Same | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-11-29 | — | — | US | disclosed |
| WO-2005034856-A2 | TARGETED DRUG-FORMALDEHYDE CONJUGATES AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275911-A1 | Targeted Drug-Formaldehyde Conjugates and Methods of Making and Using the Same | HCAR1, DHFR, FOLR1 | MEN1 3251/4885KMT2A 1881/4885THRB 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.