Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580157 | 0.89 | CCR3 (0.51) | CCR3NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5580409 | 0.83 | CCR3 (0.49) | CCR3MEN1KMT2AGAAMAPT | |
| SCHEMBL7608481 | 0.82 | CCR3 (0.66) | CCR3MEN1KMT2ACAPN1 | |
| SCHEMBL8014171 | 0.82 | CCR3 (0.66) | CCR3MEN1KMT2ACAPN1 | |
| SCHEMBL5580155 | 0.81 | CCR3 (0.48) | CCR3MEN1KMT2AGAAMAPT | |
| SCHEMBL3926458 | 0.77 | CCR3 (0.59) | CCR3CAPN1 | |
| SCHEMBL3926453 | 0.77 | CCR3 (0.59) | CCR3CAPN1 | |
| SCHEMBL8173772 | 0.76 | CCR3 (0.58) | CCR3NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL8017638 | 0.76 | CCR3 (0.58) | CCR3NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL29447178 | 0.75 | CCR3 (0.62) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249915-A1 | Inhibitors | SHISEIDO COMPANY, LTD. (JP) | 2007-10-25 | — | — | US | disclosed |