Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580147 | 0.89 | CCR3 (0.55) | CCR3MEN1KMT2AMAPTHTT | |
| SCHEMBL5580409 | 0.86 | CCR3 (0.49) | CCR3MEN1KMT2AMAPTHTT | |
| SCHEMBL5580177 | 0.86 | DEGS1 (0.49) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5580150 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL3936098 | 0.84 | NPC1 (0.54) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL5580155 | 0.84 | CCR3 (0.48) | CCR3MEN1KMT2AMAPTHTT | |
| SCHEMBL8021169 | 0.78 | CCR3 (0.47) | CCR3MEN1KMT2AMAPTHTT | |
| SCHEMBL7608481 | 0.76 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL8014171 | 0.76 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL25388151 | 0.73 | PLK1 (0.57) | MEN1KMT2AGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249915-A1 | Inhibitors | SHISEIDO COMPANY, LTD. (JP) | 2007-10-25 | — | — | US | disclosed |