Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 15/20 | 0.53 |
| ▸ | CFD | P00746 | 4/20 | 0.53 |
| ▸ | PLG | P00747 | 10/20 | 0.49 |
| ▸ | PLAT | P00750 | 4/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.48 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581069 | 0.90 | CFD (0.59) | PLAUCFDPLGPLATF11 | |
| SCHEMBL5580724 | 0.83 | PLAU (0.68) | PLAUPLGPLAT | |
| SCHEMBL5580796 | 0.81 | PLAU (0.54) | PLAUCFDPLGPLATF11 | |
| SCHEMBL5581828 | 0.80 | PLAU (0.52) | PLAUCFDPLGPLAT | |
| SCHEMBL5581092 | 0.79 | CFD (0.50) | PLAUCFDPLGPLATF11 | |
| SCHEMBL5581171 | 0.76 | PLAU (0.57) | PLAUCFDPLGPLAT | |
| SCHEMBL5580720 | 0.76 | PLAU (0.55) | PLAUCFDPLGPLAT | |
| SCHEMBL5581492 | 0.74 | PLAU (0.46) | PLAUCFDPLGPLATF11 | |
| SCHEMBL5581325 | 0.74 | FFAR1 (0.54) | PLAUCFDPLGPLAT | |
| SCHEMBL5581848 | 0.73 | PLAU (0.62) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |