Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.56 |
| ▸ | PLG | P00747 | 13/20 | 0.56 |
| ▸ | PLAT | P00750 | 8/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580761 | 0.83 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581175 | 0.78 | PLAU (0.57) | PLAUPLGPLAT | |
| SCHEMBL5581535 | 0.75 | BRD4 (0.42) | EPAS1 | |
| SCHEMBL5581425 | 0.74 | PLAU (0.76) | PLAUPLGPLAT | |
| SCHEMBL5581609 | 0.74 | PLAU (0.53) | PLAUPLGPLAT | |
| SCHEMBL5581471 | 0.74 | PLAU (0.70) | PLAUPLGPLAT | |
| SCHEMBL5581034 | 0.73 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581640 | 0.73 | PLAU (0.54) | PLAUPLGPLAT | |
| SCHEMBL5581033 | 0.73 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL16168349 | 0.72 | CA12 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |