Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 18/20 | 0.53 |
| ▸ | PLG | P00747 | 12/20 | 0.53 |
| ▸ | PLAT | P00750 | 7/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581175 | 0.86 | PLAU (0.57) | PLAUPLGPLAT | |
| SCHEMBL5581613 | 0.83 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5580672 | 0.79 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5581247 | 0.74 | PLAU (0.59) | PLAUPLGPLAT | |
| SCHEMBL5580845 | 0.74 | PLAU (0.56) | PLAUPLGPLAT | |
| SCHEMBL5581235 | 0.73 | PLAU (0.67) | PLAUPLGPLAT | |
| SCHEMBL5580761 | 0.72 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581425 | 0.72 | PLAU (0.76) | PLAUPLGPLAT | |
| SCHEMBL5581851 | 0.72 | PLAU (0.56) | PLAUPLGPLAT | |
| SCHEMBL5581209 | 0.72 | PLAU (0.81) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |