Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 3/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168349 | 0.83 | CA12 (0.47) | BRD4CREBBPCA12CA1CA7 | |
| SCHEMBL5580792 | 0.79 | CTSB (0.46) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL18664426 | 0.78 | HDAC1 (0.60) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL30504293 | 0.78 | HDAC1 (0.56) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL5581100 | 0.77 | BRD4 (0.49) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL5580845 | 0.75 | PLAU (0.56) | EPAS1 | |
| SCHEMBL16410240 | 0.75 | BRD4 (0.53) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL6285318 | 0.74 | CTSL (0.56) | BRD4CTSLGLS | |
| SCHEMBL5751130 | 0.74 | BRD9 (0.43) | HDAC1EPAS1CA12CA1CA7 | |
| SCHEMBL18664572 | 0.74 | GRM2 (0.54) | BRD4CREBBPHDAC1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |