Acetoacetic Acid

Acetoacetic Acid

SCHEMBL5581216

CC(=O)CC(=O)[O-].CCCCO[Zr+](OCCCC)OCCCC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CA1 P00915 3/20 0.38
CES2 O00748 1/20 0.36
ATM Q13315 1/20 0.34
CA2 P00918 3/20 0.34
NFKB1 P19838 1/20 0.33
CES1 P23141 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
ACHE P22303 1/20 0.32
FFAR3 O14843 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7113620 0.84 CA1 (0.36) ALDH1A1CA1ATMCA2NFKB1
SCHEMBL2671990 0.82 CA1 (0.39) ALDH1A1CA1CES2ATMCA2
Acetoacetic Acid SCHEMBL7213762 0.79 ALDH1A1 (0.42) ALDH1A1CA1CES2ATMCA2
Stearic Acid SCHEMBL813171 0.78 FABP3 (0.55) CA1CES2NFKB1CES1GPR84
Acetoacetic Acid SCHEMBL27893162 0.78 ALDH1A1 (0.41) ALDH1A1CA1CES2ATMCA2
SCHEMBL2517915 0.76 ALDH1A1 (0.39) ALDH1A1CA1CES2ATMCA2
Acetoacetic Acid SCHEMBL17685837 0.73 CA4 (0.47) ALDH1A1CA1CES2NFKB1CES1
Acetoacetic Acid SCHEMBL2208994 0.72 CA1 (0.43) CA1CES2CA2CES1FFAR3
Acetoacetic Acid SCHEMBL8164119 0.72 CA1 (0.43) CA1CES2CA2CES1FFAR3
Acetoacetic Acid SCHEMBL6709730 0.72 CA1 (0.43) CA1CES2CA2CES1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102281-A1 CURABLE SILICONE COMPOSITION DOW SILICONES CORPORATION (US) 2025-05-22 WO disclosed
CN-108174616-B Semiconductor processing sheet 琳得科株式会社 2022-03-29 CN disclosed
WO-2014017670-A1 MICROPARTICLES AND CURABLE ORGANOPOLYSILOXANE COMPOSITION CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2014-01-30 WO disclosed
EP-1127920-B1 Curable silicone composition DOW CORNING TORAY CO LTD (JP) 2007-10-31 EP disclosed
EP-1584659-A2 Curable silicone composition Dow Corning Toray Silicone Company, Ltd. (JP) 2005-10-12 EP disclosed
EP-0757080-B1 Curable organosiloxane compositions and semiconductor devices DOW CORNING TORAY SILICONE (JP) 2004-04-14 EP disclosed
EP-0985710-B1 Curable silicone composition DOW CORNING TORAY SILICONE (JP) 2003-09-24 EP disclosed
EP-0816465-B1 Silicone bonding agent for optical memory element, optical memory element, and method for manufacturing optical memory element DOW CORNING TORAY SILICONE (JP) 2003-02-26 EP disclosed
EP-0735100-B1 Curable organopolysiloxane composition DOW CORNING TORAY SILICONE (JP) 2002-10-02 EP disclosed
EP-1231242-A1 Curable organosiloxane compositions and semiconductor devices Dow Corning Toray Silicone Company Ltd. (JP) 2002-08-14 EP disclosed
EP-0985710-A1 Curable silicone composition Dow Corning Toray Silicone Company, Ltd. (JP) 2000-03-15 EP disclosed
US-5981682-A Silicon bonding agent for optical memory element, optical memory element, and method for manufacturing optical memory element DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-11-09 US disclosed
US-5804631-A CURING A MIXTURE OF AN ALKOXY-SUBSTITUTED ORGANOPOLYSILOXANE, AN ALKENYL-SUBSTITUTED ORGANOPOLYSILOXANE AND AN ORGANOPOLYSILOXANE WITH AT LEAST TWO SILICON-BONDED HYDROGEN ATOMS DOW CORNING TORAY SILICONE CO., LTD. (JP) 1998-09-08 US disclosed
EP-0818520-A2 Method for manufacturing bonded structure Dow Corning Toray Silicone Co., Ltd. (JP) 1998-01-14 EP disclosed
EP-0816465-A2 Silicone bonding agent for optical memory element, optical memory element, and method for manufacturing optical memory element Dow Corning Toray Silicone Company Limited (JP) 1998-01-07 EP disclosed
US-5684110-A Silicone rubber composition for formed-in-place gaskets DOW CORNING TORAY SILICONE CO., LTD. (JP) 1997-11-04 US disclosed
US-5625022-A Curable organopolysiloxane composition DOW CORNING TORAY SILICONE CO., LTD. (JP) 1997-04-29 US disclosed
EP-0757080-A2 Curable organosiloxane compositions and semiconductor devices Dow Corning Toray Silicone Company Ltd. (JP) 1997-02-05 EP disclosed
EP-0752450-A1 Silicone rubber composition for formed-in-place gaskets Dow Corning Toray Silicone Company Ltd. (JP) 1997-01-08 EP disclosed
EP-0735100-A2 Curable organopolysiloxane composition Dow Corning Toray Silicone Company, Limited (JP) 1996-10-02 EP disclosed