Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.52 |
| ▸ | PLG | P00747 | 12/20 | 0.52 |
| ▸ | PLAT | P00750 | 5/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581853 | 0.80 | PLAU (0.49) | PLAUPLGPLAT | |
| SCHEMBL5581176 | 0.79 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581602 | 0.78 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5581247 | 0.75 | PLAU (0.59) | PLAUPLGPLAT | |
| SCHEMBL5581907 | 0.73 | PLAU (0.49) | PLAUPLGPLAT | |
| SCHEMBL5580814 | 0.72 | PLAU (0.71) | PLAUPLGPLAT | |
| SCHEMBL5581613 | 0.72 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5580673 | 0.72 | PLAU (0.45) | PLAUPLGPLAT | |
| SCHEMBL5581983 | 0.70 | PLAU (0.74) | PLAUPLGPLAT | |
| SCHEMBL5581466 | 0.69 | PLAU (0.86) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |