SCHEMBL5581602

SCHEMBL5581602

C=Cc1nc(Oc2cc(C)cc(-c3cccc(N(C)C(=O)O)c3)c2)c(F)cc1F

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.47
PLG P00747 14/20 0.47
PLAT P00750 8/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581853 0.86 PLAU (0.49) PLAUPLGPLAT
SCHEMBL5581599 0.81 PLAU (0.54) PLAUPLGPLAT
SCHEMBL5581249 0.78 PLAU (0.52) PLAUPLGPLAT
SCHEMBL5581411 0.78 PLAU (0.51) PLAUPLGPLAT
SCHEMBL5581176 0.75 PLAU (0.52) PLAUPLGPLAT
SCHEMBL5580673 0.71 PLAU (0.45) PLAUPLGPLAT
SCHEMBL5581613 0.70 PLAU (0.51) PLAUPLGPLAT
SCHEMBL5581907 0.69 PLAU (0.49) PLAUPLGPLAT
SCHEMBL5581851 0.66 PLAU (0.56) PLAUPLGPLAT
SCHEMBL5581267 0.65 PLAU (0.75) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed