Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.45 |
| ▸ | PLG | P00747 | 12/20 | 0.45 |
| ▸ | PLAT | P00750 | 7/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581176 | 0.84 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5580672 | 0.83 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5581613 | 0.77 | PLAU (0.51) | PLAUPLGPLAT | |
| SCHEMBL5581015 | 0.73 | PLAU (0.64) | PLAUPLGPLAT | |
| SCHEMBL5581853 | 0.72 | PLAU (0.49) | PLAUPLGPLAT | |
| SCHEMBL5581249 | 0.72 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581602 | 0.71 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5580722 | 0.71 | PLAU (0.62) | PLAUPLGPLAT | |
| SCHEMBL5580761 | 0.69 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581505 | 0.68 | PLAU (0.61) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |