SCHEMBL5581293

SCHEMBL5581293

CCC(C)(c1ccc(Oc2ccc(C(=O)O)cc2)c(C)c1)c1ccc(Oc2ccc(C(=O)O)cc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.50
NPC1 O15118 1/20 0.49
POLB P06746 1/20 0.49
CYP2C9 P11712 1/20 0.49
RAB9A P51151 1/20 0.49
LPAR1 Q92633 5/20 0.46
LPAR5 Q9H1C0 5/20 0.46
RXRB P28702 2/20 0.44
NR4A2 P43354 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
FFAR1 O14842 1/20 0.43
VDR P11473 1/20 0.43
TTR P02766 2/20 0.43
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
KMT2A Q03164 1/20 0.42
RXRG P48443 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581310 0.86 RXRA (0.55) RXRANPC1POLBCYP2C9RAB9A
SCHEMBL5581812 0.84 NPC1 (0.57) RXRANPC1POLBCYP2C9RAB9A
SCHEMBL5581391 0.83 NPC1 (0.48) RXRANPC1POLBCYP2C9RAB9A
SCHEMBL19951345 0.82 FFAR1 (0.57) RXRARAB9ALPAR1LPAR5RXRB
SCHEMBL2894490 0.80 MAPT (0.55) NPC1POLBRAB9AFFAR1VDR
SCHEMBL5582063 0.80 RXRA (0.51) RXRALPAR1LPAR5RXRBMRGPRX4
SCHEMBL5581740 0.77 SRD5A2 (0.58) RXRALPAR1LPAR5RXRBTTR
SCHEMBL9578939 0.77 MEN1 (0.59) RXRARXRBNR4A2MEN1CYP1A2
SCHEMBL5157346 0.77 RXRA (0.41) RXRANPC1POLBCYP2C9RAB9A
SCHEMBL5157350 0.77 RXRA (0.41) RXRANPC1POLBCYP2C9RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
EP-1698460-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2006-09-06 EP disclosed
US-20060134407-A1 Adhesive sheet and layered product TEIJIN LIMITED (JP) 2006-06-22 US disclosed
EP-1589086-A1 ADHESIVE SHEET AND LAYERED PRODUCT TEIJIN LIMITED (JP) 2005-10-26 EP disclosed