SCHEMBL5581500

SCHEMBL5581500

CCCCCCCCCCCCCCCC(CC(C)(C)O[SiH3])N(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
PLA2G1B P04054 1/20 0.30
PLA2G2A P14555 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511673 0.75 LMNA (0.32) LMNACA2
SCHEMBL28416093 0.75 LMNA (0.32) LMNACA2
SCHEMBL28413451 0.75 LMNA (0.32) LMNACA2
SCHEMBL28416438 0.75 LMNA (0.32) LMNACA2
SCHEMBL23437461 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A
SCHEMBL22096531 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A
SCHEMBL22401146 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A
SCHEMBL23437458 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A
SCHEMBL22401186 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A
SCHEMBL20882132 0.74 TSHR (0.44) LMNAPLA2G1BPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070010004-A1 Micellar systems ROCHE MADISON INC. 2007-01-11 US disclosed
US-7091041-B2 Micellar systems MIRUS BIO CORPORATION (US) 2006-08-15 US disclosed
US-20040023393-A1 Micellar systems ROCHE MADISON INC. 2004-02-05 US disclosed
US-6673612-B2 GENERATION OF MICELLE FOR THE TRANSFER OF BIOPOLYMERS TO CELLS; FORM CATIONIC REVERSE MICELLE USING AMPHIPATHIC MOLECULES, INSERT BIPOLYMER, ADJUST THE CHARGE OF MICELLE , TRANSFER TO CELLS MIRUS CORPORATION 2004-01-06 US disclosed
US-20030027339-A1 Micellar systems ROCHE MADISON INC. 2003-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010004-A1 Micellar systems POLRMT, NSUN3, NSUN2 LMNA 192/4885PLA2G1B 1206/4885PLA2G2A 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.