Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572109 | 0.86 | HDAC1 (0.52) | BRD4CREBBPGAAGLSNQO2 | |
| SCHEMBL5580714 | 0.84 | ACACB (0.47) | ACACBCYP1A2CYP3A4CYP2C9ACACA | |
| SCHEMBL30151702 | 0.81 | GLS (0.52) | CYP1A2CYP3A4BRD4CREBBPGAA | |
| SCHEMBL1111369 | 0.81 | GLS (0.52) | CYP1A2CYP3A4BRD4CREBBPGAA | |
| SCHEMBL5581659 | 0.81 | ACACB (0.39) | ACACBCYP1A2CYP3A4CYP2C9ACACA | |
| SCHEMBL3847043 | 0.80 | BRD4 (0.47) | ACACBCYP1A2CYP3A4CYP2C9ACACA | |
| SCHEMBL30504293 | 0.79 | HDAC1 (0.56) | BRD4CREBBPGLSHDAC1NAMPT | |
| SCHEMBL2568359 | 0.78 | HDAC1 (0.56) | BRD4CREBBPGLSNQO2HDAC1 | |
| SCHEMBL2570147 | 0.78 | HDAC1 (0.62) | CYP3A4CYP2C9BRD4CREBBPGAA | |
| SCHEMBL6285318 | 0.78 | CTSL (0.56) | BRD4GAAGLSCTSLKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |