SCHEMBL5581586

SCHEMBL5581586

N#CCc1cc(Oc2cccc(-c3ccccc3C(=O)O)n2)cc(-c2cccc(CN)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLAU P00749 19/20 0.47
PLG P00747 13/20 0.47
PLAT P00750 6/20 0.42
CFD P00746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581364 0.90 PLAU (0.50) PLAUPLGPLATCFD
Hydrochloric Acid SCHEMBL5580908 0.88 PLAU (0.56) PLAUPLGPLATCFD
SCHEMBL5580874 0.87 PLAU (0.51) PLAUPLGPLAT
SCHEMBL5581641 0.87 PLAU (0.52) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5581873 0.84 PLAU (0.47) PLAUPLGPLAT
SCHEMBL5580944 0.82 PLAU (0.48) PLAUPLGPLATCFD
SCHEMBL5581648 0.80 PLAU (0.49) PLAUPLGPLAT
SCHEMBL5581446 0.80 PLAU (0.47) PLAUPLGPLAT
SCHEMBL5581047 0.79 PLAU (0.49) PLAUPLGPLAT
SCHEMBL5580907 0.79 PLAU (0.54) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed