Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 17/20 | 0.48 |
| ▸ | PLG | P00747 | 12/20 | 0.48 |
| ▸ | PLAT | P00750 | 5/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5581985 | 0.92 | PLAU (0.42) | PLAUPLGPLATIKBKBCHUK | |
| SCHEMBL5580874 | 0.86 | PLAU (0.51) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5580908 | 0.85 | PLAU (0.56) | PLAUPLGPLATCFD | |
| SCHEMBL5581641 | 0.84 | PLAU (0.52) | PLAUPLGPLAT | |
| SCHEMBL5581586 | 0.82 | PLAU (0.47) | PLAUPLGPLATCFD | |
| SCHEMBL5581364 | 0.82 | PLAU (0.50) | PLAUPLGPLATCFD | |
| Hydrochloric Acid SCHEMBL5581873 | 0.81 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5581446 | 0.79 | PLAU (0.47) | PLAUPLGPLAT | |
| SCHEMBL5580907 | 0.78 | PLAU (0.54) | PLAUPLGPLAT | |
| Hydrochloric Acid SCHEMBL5581245 | 0.77 | PLAU (0.56) | PLAUPLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |