SCHEMBL5580672

SCHEMBL5580672

N#Cc1cc(Oc2nc(-c3ccccc3C=O)c(F)cc2F)cc(-c2cccc(CNC(=O)O)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 19/20 0.51
PLG P00747 13/20 0.51
PLAT P00750 8/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581175 0.85 PLAU (0.57) PLAUPLGPLAT
SCHEMBL5580673 0.83 PLAU (0.45) PLAUPLGPLAT
SCHEMBL5580761 0.81 PLAU (0.52) PLAUPLGPLAT
SCHEMBL5581015 0.79 PLAU (0.64) PLAUPLGPLAT
SCHEMBL5581609 0.79 PLAU (0.53) PLAUPLGPLAT
SCHEMBL5580722 0.78 PLAU (0.62) PLAUPLGPLAT
SCHEMBL5581247 0.73 PLAU (0.59) PLAUPLGPLAT
SCHEMBL5581505 0.73 PLAU (0.61) PLAUPLGPLAT
SCHEMBL5580845 0.72 PLAU (0.56) PLAUPLGPLAT
SCHEMBL5581049 0.72 PLAU (0.60) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed