SCHEMBL5581616

SCHEMBL5581616

Cc1cc(Cc2cc(C)c(Oc3ccc(C(=O)O)cc3)c(C)c2)cc(C)c1Oc1ccc(C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.57
LPAR1 Q92633 5/20 0.54
LPAR5 Q9H1C0 5/20 0.54
RXRA P19793 2/20 0.47
PARP15 Q460N3 1/20 0.46
PARP10 Q53GL7 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
AMY1A P0DUB6 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846809 0.85 LPAR1 (0.51) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL30498840 0.82 HPGD (0.52) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL5581740 0.81 SRD5A2 (0.58) SRD5A2LPAR1LPAR5RXRARXRB
SCHEMBL5582339 0.81 LPAR1 (0.48) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL16691902 0.80 SRD5A2 (0.48) SRD5A2HPGDHTTTHRATHRB
SCHEMBL10685959 0.80 LPAR1 (0.68) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL5581716 0.79 KMT2A (0.49) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL5581391 0.79 NPC1 (0.48) SRD5A2LPAR1LPAR5RXRAPARP15
SCHEMBL5581537 0.77 SRD5A2 (0.89) SRD5A2RXRAPARP15PARP10CA1
SCHEMBL1732395 0.76 ALDH1A1 (0.50) HPGDNPC1POLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
EP-1698460-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2006-09-06 EP disclosed
US-20060134407-A1 Adhesive sheet and layered product TEIJIN LIMITED (JP) 2006-06-22 US disclosed
EP-1589086-A1 ADHESIVE SHEET AND LAYERED PRODUCT TEIJIN LIMITED (JP) 2005-10-26 EP disclosed