SCHEMBL5582339

SCHEMBL5582339

Cc1cc(C(C)(C)c2cc(C)c(Oc3ccc(C(=O)O)cc3)c(C)c2)cc(C)c1Oc1ccc(C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 3/20 0.48
LPAR5 Q9H1C0 3/20 0.48
RXRA P19793 6/20 0.47
PARP15 Q460N3 1/20 0.46
PARP10 Q53GL7 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
SRD5A2 P31213 2/20 0.45
RXRB P28702 4/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
RXRG P48443 2/20 0.43
NR4A2 P43354 1/20 0.43
AMY1A P0DUB6 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581391 0.85 NPC1 (0.48) LPAR1LPAR5RXRAPARP15PARP10
SCHEMBL2846809 0.85 LPAR1 (0.51) LPAR1LPAR5RXRAPARP15PARP10
SCHEMBL17879947 0.84 ELANE (0.49) LPAR1LPAR5SRD5A2POLB
SCHEMBL30498840 0.82 HPGD (0.52) LPAR1LPAR5RXRAPARP15PARP10
SCHEMBL5581310 0.81 RXRA (0.55) LPAR1LPAR5RXRAPARP15PARP10
SCHEMBL8656957 0.81 ALDH1A1 (0.49) RXRBPOLB
SCHEMBL1634704 0.81 PARP15 (0.58) RXRAPARP15PARP10CA1CA2
SCHEMBL5581616 0.81 SRD5A2 (0.57) LPAR1LPAR5RXRAPARP15PARP10
SCHEMBL16691899 0.80 TUBB4A (0.44) SRD5A2HPGDHTTRAB9AKMT2A
SCHEMBL16691892 0.80 TUBB4A (0.48) PARP10CA1CA2HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
EP-1698460-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2006-09-06 EP disclosed
US-20060134407-A1 Adhesive sheet and layered product TEIJIN LIMITED (JP) 2006-06-22 US disclosed
EP-1589086-A1 ADHESIVE SHEET AND LAYERED PRODUCT TEIJIN LIMITED (JP) 2005-10-26 EP disclosed