⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967495 | 0.78 | — | — | |
| SCHEMBL11153273 | 0.78 | MCL1 (0.33) | — | |
| SCHEMBL29838200 | 0.77 | MCL1 (0.39) | — | |
| SCHEMBL27343778 | 0.75 | — | — | |
| SCHEMBL5094060 | 0.74 | — | — | |
| SCHEMBL10833402 | 0.74 | — | — | |
| SCHEMBL10366551 | 0.74 | DAO (0.37) | — | |
| SCHEMBL4409393 | 0.74 | — | — | |
| SCHEMBL28764956 | 0.71 | MCL1 (0.34) | — | |
| SCHEMBL5698996 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300784-B2 | Nitrile hydratase and a method for producing amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-6900037-B2 | Method for producing amide compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20040209345-A1 | Nitrile Hydratase and a Method for Producing Amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-21 | — | — | US | disclosed |
| US-20030124691-A1 | Method for producing amide compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-03 | — | — | US | disclosed |
| EP-1266962-A2 | Method for producing amide compounds | Daicel Chemical Industries, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
| EP-0666320-B1 | Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms | MITSUBISHI RAYON CO (JP) | 2000-12-20 | — | — | EP | disclosed |
| EP-0711836-B1 | Method of producing optically active alpha-hydroxy acid or alpha-hydroxyamide | MITSUBISHI RAYON CO (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5756306-A | HYDROLYSIS OF COMPOUNDS USING MICROORGAMISMS TO FORM ALPHA HYDROXY ACIDS OR AMIDES | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5736385-A | NITRILASE OR NITRILE HYDRATASE HYDROLYSIS OF A CYANOHYDRIN WHILE AUTOMATICALLY CONTROLLING CYANOHYDRIN CONCENTRATION | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0773297-A2 | Process for producing alfa-hydroxy acid or alfa-hydroxyamide by microorganism | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0711836-A1 | Method of producing optically active alpha-hydroxy acid or alpha-hydroxyamide | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5508181-A | REACTING AN ALPHA-HYDROXYNITRILE (OR MIXTURE WITH AN ALDEHYDE) WITH HYDROGEN CYANIDE IN PRESENCE OF PHOSPHITE OR HYPOPHOSPHITE IONS | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0666320-A2 | Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-08-09 | — | — | EP | disclosed |