Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256481 | 0.85 | ELANE (0.41) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29267500 | 0.84 | CHRM5 (0.36) | SMN1; SMN2LMNAMAPTALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10687532 | 0.84 | ELANE (0.40) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11302309 | 0.83 | ELANE (0.37) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8942078 | 0.83 | ALDH1A1 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL14135088 | 0.81 | ELANE (0.38) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1900060 | 0.80 | ALDH1A1 (0.40) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16594997 | 0.80 | ALDH1A1 (0.38) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9011226 | 0.80 | ELANE (0.40) | ELANESMN1; SMN2LMNANPSR1MAPT | |
| SCHEMBL5345224 | 0.80 | ELANE (0.37) | ELANECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214752-B2 | Homopolymers which exhibit a high level of photo-inducable birefringence | BAYER MATERIALSCIENCE AG (DE) | 2007-05-08 | — | — | US | disclosed |
| EP-0981558-B1 | HOMOPOLYMERS WITH HIGH PHOTOINDUCEABLE DOUBLE REFRACTION | BAYER MATERIALSCIENCE AG (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-6875833-B2 | Monomers and homopolymers, having high photoinduceable double refraction, prepared therefrom | BAYER AKTIENGESELLSCHAFT (DE) | 2005-04-05 | — | — | US | disclosed |
| US-20050070678-A1 | Homopolymers which exhibit a high level of photo-inducable birefringence | BERNETH HORST (DE) | 2005-03-31 | — | — | US | disclosed |
| US-20030083449-A1 | Monomers and homopolymers, having high photoinduceable double refraction, prepared therefrom | COVESTRO DEUTSCHLAND AG (DE) | 2003-05-01 | — | — | US | disclosed |
| US-6441113-B1 | HOMOPOLYMER OF A (METH)ACRYLATE ESTER OF AN AZOBENZENE-CONTAINING TRINUCLEAR GROUP OF GIVEN FORMULA; HIGH LEVEL OF BIREFRINGENCE INDUCED BY IRRADIATION; USE IN STORAGE OF OPTICAL INFORMATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070678-A1 | Homopolymers which exhibit a high level of photo-inducable birefringence | PCNA, SMC4, PARN | ELANE 2475/4885CHRNB2 2807/4885CHRNB4 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.