SCHEMBL558234

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3575254	0.78	ADORA1 (0.39)	AKT2AKT1PSMB5TDO2ALOX15
	SCHEMBL557658	0.76	ALDH1A1 (0.40)	AKT2AKT1TDO2CYP2A6NPC1
	SCHEMBL558235	0.72	PDE10A (0.43)	AKT2AKT1MEN1NPC1KMT2A
	SCHEMBL10677727	0.72	ENPP1 (0.40)	TDO2MEN1NPC1KMT2ARAB9A
	SCHEMBL2439327	0.69	CYP2A6 (0.45)	CYP2A6MEN1KMT2AMETAP2
	SCHEMBL18952722	0.69	KDM4E (0.47)	MEN1NPC1KMT2ARAB9AKDM4E
	SCHEMBL18952645	0.69	ADORA1 (0.39)	MEN1NPC1KMT2ARAB9AALDH1A1
	SCHEMBL2439329	0.68	CCR1 (0.52)	CYP2A6NPC1RAB9ATP53MAPT
	SCHEMBL4316992	0.67	CYP2A6 (0.36)	CYP2A6NPC1RAB9AKDM4EMAPT
	SCHEMBL16826104	0.67	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.