Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 7/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2982204 | 1.00 | AKR1B10 (0.39) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13592863 | 0.96 | BACE1 (0.38) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2983660 | 0.94 | AKR1C3 (0.43) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2983664 | 0.94 | AKR1C3 (0.43) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13592925 | 0.91 | AKR1B10 (0.39) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL4398208 | 0.90 | PLK1 (0.37) | PLK1PLK3MAPTMEN1KMT2A | |
| SCHEMBL4560751 | 0.89 | PLK1 (0.41) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2982288 | 0.89 | PLK1 (0.41) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13686562 | 0.89 | AKR1B10 (0.35) | AKR1B10AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2992276 | 0.88 | PLK1 (0.42) | PLK1PLK3MAPTCDK2IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270437-A1 | Benzimidazole Thiophene Compounds | CHEUNG MUI | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270437-A1 | Benzimidazole Thiophene Compounds | ABCB1, CYP3A5, ABCG2 | AKR1B10 1406/4885AKR1B1 1979/4885AKR1C4 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.