⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441412 | 0.90 | ADORA2A (0.35) | — | |
| SCHEMBL3637089 | 0.87 | BRD4 (0.30) | — | |
| SCHEMBL2028468 | 0.83 | ADORA2B (0.38) | — | |
| SCHEMBL343674 | 0.81 | POLB (0.45) | — | |
| SCHEMBL29674590 | 0.80 | TYMP (0.39) | — | |
| SCHEMBL15786367 | 0.80 | TYMP (0.39) | — | |
| SCHEMBL2054229 | 0.80 | TYMP (0.39) | — | |
| SCHEMBL29449394 | 0.80 | TYMP (0.39) | — | |
| SCHEMBL23881919 | 0.79 | PRMT6 (0.34) | — | |
| SCHEMBL17222397 | 0.79 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658608-B2 | Modified triple-helix forming oligonucleotides for targeted mutagenesis | YALE UNIVERSITY (US) | 2014-02-25 | — | — | US | disclosed |
| US-20070219122-A1 | MODIFIED TRIPLE-HELIX FORMING OLIGONUCLEOTIDES FOR TARGETED MUTAGENESIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-20 | — | — | US | disclosed |