SCHEMBL558285

SCHEMBL558285

CCCCCCCC([SiH2]C(OC)OC)[SiH2]C(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.37
LMNA P02545 1/20 0.37
DNM1 Q05193 2/20 0.36
PLA2G1B P04054 1/20 0.35
PLA2G2A P14555 1/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
OPRM1 P35372 1/20 0.34
SMPD1 P17405 3/20 0.34
FDPS P14324 3/20 0.33
GPR84 Q9NQS5 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1819304 0.98 OPRM1 (0.36) ZDHHC7LMNADNM1PLA2G1BPLA2G2A
SCHEMBL556911 0.81 OPRM1 (0.38) ZDHHC7LMNADNM1PLA2G1BPLA2G2A
SCHEMBL1123104 0.81 OPRM1 (0.38) ZDHHC7LMNADNM1PLA2G1BPLA2G2A
SCHEMBL1123631 0.78 OPRM1 (0.39) LMNADNM1PLA2G1BPLA2G2ATHRB
SCHEMBL1820600 0.77 OPRM1 (0.33) LMNADNM1PLA2G1BPLA2G2AOPRM1
SCHEMBL1819451 0.77 OPRM1 (0.38) LMNADNM1PLA2G1BPLA2G2AOPRM1
SCHEMBL7070388 0.70 OPRM1 (0.39) LMNADNM1PLA2G1BPLA2G2ATSHR
SCHEMBL826118 0.69 SMPD1 (0.50) ZDHHC7LMNADNM1TSHRTHRB
SCHEMBL531229 0.69 SMPD1 (0.50) ZDHHC7LMNADNM1TSHRTHRB
SCHEMBL18165672 0.69 TSHR (0.44) ZDHHC7LMNADNM1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
EP-1626998-A1 METHOD FOR PRODUCING AQUEOUS POLYMER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2006-02-22 EP disclosed
WO-2004101632-A1 METHOD FOR PRODUCING AQUEOUS POLYMER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2004-11-25 WO disclosed
EP-0304416-A1 Process for preparing microcapsules or micromatrix particles F. Joh. KWIZDA Gesellschaft m.b.H. (AT) 1989-02-22 EP disclosed