SCHEMBL1819451

SCHEMBL1819451

CCCCCC([SiH2]C(OC(C)C)OC(C)C)[SiH2]C(OC(C)C)OC(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.38
CA1 P00915 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32
TP53 P04637 1/20 0.31
LMNA P02545 3/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
PLA2G1B P04054 1/20 0.31
PLA2G2A P14555 1/20 0.31
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1819304 0.78 OPRM1 (0.36) OPRM1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL1123631 0.77 OPRM1 (0.39) OPRM1TP53LMNAPLA2G1BPLA2G2A
SCHEMBL558285 0.77 ZDHHC7 (0.37) OPRM1SPHK1LMNAPLA2G1BPLA2G2A
SCHEMBL1820600 0.75 OPRM1 (0.33) OPRM1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL556911 0.75 OPRM1 (0.38) OPRM1LMNAPLA2G1BPLA2G2ADNM1
SCHEMBL1123104 0.75 OPRM1 (0.38) OPRM1LMNAPLA2G1BPLA2G2ADNM1
Hexane SCHEMBL7374893 0.71 TSHR (0.47) OPRM1LMNADNM1
Hexane SCHEMBL5781731 0.71 TSHR (0.47) OPRM1LMNADNM1
Hexane SCHEMBL295692 0.71 TSHR (0.47) OPRM1LMNADNM1
SCHEMBL11232060 0.70 OPRM1 (0.46) OPRM1CA1SPHK1TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
CN-101829600-B Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2012-08-29 CN disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed
CN-101829600-A Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2010-09-15 CN disclosed