Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677629 | 0.74 | ALDH1A1 (0.42) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL27343773 | 0.70 | PKM (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL20298901 | 0.69 | ALDH1A1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL10682534 | 0.69 | ALDH1A1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL30518734 | 0.69 | HTT (0.40) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL20298897 | 0.68 | S1PR1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL22026830 | 0.68 | S1PR1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL824956 | 0.68 | S1PR1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL824959 | 0.68 | S1PR1 (0.41) | HTTMEN1KMT2AS1PR1S1PR3 | |
| SCHEMBL3363603 | 0.67 | PKM (0.38) | HTTMEN1KMT2AS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740189-B1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NAT RECH SCIENT (FR) | 2012-06-13 | — | — | EP | disclosed |
| EP-1740189-A1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005099718-A1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2005-10-27 | — | — | WO | disclosed |