Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.46 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583406 | 0.82 | VCAM1 (0.46) | MAPK1TSHRLMNAMAPTALDH1A1 | |
| SCHEMBL3253882 | 0.81 | TSHR (0.51) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL31633570 | 0.80 | CYP1A2 (0.56) | MAPK1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL5583438 | 0.80 | CYP1A2 (0.56) | MAPK1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL343287 | 0.79 | TSHR (0.43) | MAPK1TSHRPDE7ALMNAMAPT | |
| SCHEMBL12165493 | 0.79 | TDP1 (0.48) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL9371394 | 0.79 | PDE7A (0.36) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL9406614 | 0.78 | VCAM1 (0.46) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL5583440 | 0.78 | MAPT (0.51) | MAPK1TSHRL3MBTL1APPMAPT | |
| SCHEMBL27382568 | 0.78 | TSHR (0.42) | MAPK1TSHRPDE7APDE7BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | MAPK1 2819/4885TSHR 1938/4885PDE7A 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.