Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133136 | 0.85 | TP53 (0.50) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7718349 | 0.85 | TP53 (0.50) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7721723 | 0.85 | TP53 (0.50) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1198598 | 0.85 | TP53 (0.59) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5549311 | 0.79 | TP53 (0.44) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL19585953 | 0.78 | ALDH1A1 (0.54) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19586826 | 0.78 | ALDH1A1 (0.54) | TP53MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5545154 | 0.78 | TP53 (0.53) | TP53MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL23397555 | 0.77 | KMT2A (0.48) | TP53MEN1KMT2AMAPTLMNA | |
| SCHEMBL29042815 | 0.77 | TP53 (0.53) | TP53MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761508-A1 | STEREOSPECIFIC ANXIOLYTIC AND ANTICONVULSANT AGENTS WITH REDUCED MUSCLE-RELAXANT, SEDATIVE-HYPNOTIC AND ATAXIC EFFECTS | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006004945-A1 | STEREOSPECIFIC ANXIOLYTIC AND ANTICONVULSANT AGENTS WITH REDUCED MUSCLE-RELAXANT, SEDATIVE-HYPNOTIC AND ATAXIC EFFECTS | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2006-01-12 | — | — | WO | disclosed |