Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284441 | 0.86 | NPC1 (0.54) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL14284448 | 0.79 | HCRTR1 (0.41) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL14284440 | 0.78 | TAS1R3 (0.40) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL14284407 | 0.78 | TAS1R3 (0.46) | TAS1R3TAS1R1ADORA2AKMT2AMEN1 | |
| SCHEMBL5583588 | 0.78 | TAS1R3 (0.53) | PDE4APDE4BPDE4CPDE4DTAS1R3 | |
| SCHEMBL5583854 | 0.76 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5583701 | 0.76 | ALDH1A1 (0.50) | TAS1R3TAS1R1KMT2AMEN1TAS1R2 | |
| SCHEMBL5583860 | 0.75 | ALDH1A1 (0.52) | TAS1R3TAS1R1KMT2AMEN1TAS1R2 | |
| SCHEMBL5583725 | 0.75 | ALDH1A1 (0.52) | TAS1R3TAS1R1KMT2AMEN1TAS1R2 | |
| SCHEMBL5583720 | 0.75 | ALDH1A1 (0.52) | TAS1R3TAS1R1KMT2AMEN1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |