Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166467 | 0.81 | FEN1 (0.71) | FEN1ALDH1A1AKR1B1KMT2ATSHR | |
| SCHEMBL5996812 | 0.79 | FEN1 (0.53) | FEN1ALDH1A1AKR1B1KMT2ASMN1; SMN2 | |
| SCHEMBL19494060 | 0.79 | FEN1 (0.53) | FEN1ALDH1A1AKR1B1KMT2ASMN1; SMN2 | |
| SCHEMBL27926380 | 0.79 | FEN1 (0.53) | FEN1ALDH1A1AKR1B1CYP2C19KMT2A | |
| SCHEMBL10120278 | 0.79 | ERCC5 (0.62) | FEN1NR4A2ALDH1A1AKR1B1GAA | |
| SCHEMBL10576213 | 0.78 | ERCC5 (0.59) | FEN1NR4A2ALDH1A1GAACYP2C19 | |
| SCHEMBL11701099 | 0.77 | NR4A2 (0.46) | FEN1NR4A2ALDH1A1AKR1B1GAA | |
| SCHEMBL11702836 | 0.77 | ALDH1A1 (0.56) | NR4A2ALDH1A1AKR1B1GAACYP2C19 | |
| SCHEMBL6930314 | 0.76 | TYK2 (0.54) | NR4A2ALDH1A1GAACYP2C19KMT2A | |
| SCHEMBL12431212 | 0.76 | FEN1 (0.59) | FEN1ALDH1A1AKR1B1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7193108-B2 | Phenylpropionic acid derivatives | AJINOMOTO CO., INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7193108-B2 | Phenylpropionic acid derivatives | AJINOMOTO CO., INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-7193108-B2 | Phenylpropionic acid derivatives | AJINOMOTO CO., INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20040236147-A1 | Phenylpropionic acid derivatives | AJINOMOTO CO. INC (JP) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236147-A1 | Phenylpropionic acid derivatives | VCAM1, ICAM1, SELP | FEN1 4400/4885NR4A2 1226/4885ALDH1A1 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.