SCHEMBL5583700

SCHEMBL5583700

Cc1ccc(Oc2ccc(N)cc2C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.52
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
POLB P06746 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
AR P10275 7/20 0.47
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
KCNH2 Q12809 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
RAB9A P51151 1/20 0.44
LMNA P02545 1/20 0.41
ATM Q13315 1/20 0.41
MAPK1 P28482 1/20 0.40
SYK P43405 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13114513 0.95 TEAD4 (0.47) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL26037439 0.95 TEAD4 (0.46) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL649657 0.92 TSHR (0.53) ALDH1A1MAPTPOLBTDP1AR
SCHEMBL29352455 0.92 TSHR (0.53) ALDH1A1MAPTPOLBTDP1AR
SCHEMBL26037417 0.91 AR (0.42) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL14865703 0.91 AR (0.45) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL29448858 0.90 TSHR (0.52) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL1352801 0.90 TSHR (0.52) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL7187793 0.90 TSHR (0.52) TEAD4ALDH1A1MAPTPOLBTDP1
SCHEMBL12689579 0.89 POLB (0.44) TEAD4ALDH1A1MAPTPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140228512-A1 POLYIMIDES, COATING COMPOSITION FORMED THEREFROM AND USE THEREOF ETERNAL CHEMICAL CO., LTD. (TW) 2014-08-14 US disclosed
US-7820253-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS (US) 2010-10-26 US disclosed
US-7820253-B2 Poly(aryletherimides) for negative birefringent films for LCDs AKRON POLYMER SYSTEMS (US) 2010-10-26 US disclosed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US disclosed
US-20090197019-A1 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS THE UNIVERSITY OF AKRON (US) 2009-08-06 US disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed