SCHEMBL14865703

SCHEMBL14865703

Cc1ccc(Oc2ccc(Oc3ccc(N)cc3C(F)(F)F)cc2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.45
TEAD4 Q15561 1/20 0.42
ALDH1A1 P00352 3/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39
SYK P43405 1/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15831196 0.96 AR (0.43) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL12689579 0.93 POLB (0.44) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL26037439 0.93 TEAD4 (0.46) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL14865664 0.93 POLB (0.44) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL5583700 0.91 TEAD4 (0.52) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL14865684 0.90 L3MBTL1 (0.40) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL12259242 0.90 AR (0.47) ARMAPTL3MBTL1RAB9AHTR2A
SCHEMBL12689646 0.89 GLA (0.41) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL26037417 0.89 AR (0.42) ARTEAD4ALDH1A1POLBMAPT
SCHEMBL27821176 0.88 AR (0.44) ARPOLBMAPTGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170298198-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES SUMITOMO BAKELITE CO., LTD. (JP) 2017-10-19 US disclosed
US-20160369053-A1 POLYIMIDE RESIN AND METAL-CLAD LAMINATE COMPRISING THE SAME ETERNAL MATERIALS CO., LTD. (TW) 2016-12-22 US disclosed
US-20160311970-A1 INSERTION POLYNORBORNENE-BASED THERMOSET RESINS CLAVERIE, Jérôme (CA) 2016-10-27 US disclosed
US-20160208096-A1 SOLUTION OF AROMATIC POLYAMIDE FOR PRODUCING DISPLAY ELEMENT, OPTICAL ELEMENT, ILLUMINATION ELEMENT OR SENSOR ELEMENT AKRON POLYMER SYSTEMS, INC. (US) 2016-07-21 US disclosed
US-20160111696-A1 METHOD FOR MAKING POLYIMIDE MICROPOROUS SEPARATOR TSINGHUA UNIVERSITY (CN) 2016-04-21 US disclosed
US-20140175683-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2014-06-26 US disclosed
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed