SCHEMBL5583726

SCHEMBL5583726

COc1ccnc(C(=O)NCCC2CCCCC2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRA P16234 3/20 0.50
POLB P06746 1/20 0.43
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 3/20 0.42
HPGD P15428 1/20 0.42
LDLR P01130 1/20 0.42
KIT P10721 2/20 0.41
CHRM4 P08173 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 2/20 0.39
MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583815 0.88 TDP1 (0.54) POLBKMT2AHPGDTDP1MEN1
SCHEMBL15480783 0.84 ALDH1A1 (0.52) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL5583725 0.84 ALDH1A1 (0.52) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL5583860 0.84 ALDH1A1 (0.52) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL5583720 0.84 ALDH1A1 (0.52) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL5583707 0.84 ALDH1A1 (0.52) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL5583701 0.83 ALDH1A1 (0.50) PDGFRANPC1RAB9AL3MBTL1KMT2A
SCHEMBL14284531 0.82 EGLN1 (0.42) POLBKMT2AHPGDPDE4APDE4B
SCHEMBL5583854 0.80 TAS1R3 (0.48) PDGFRANPC1RAB9AL3MBTL1HPGD
SCHEMBL5583588 0.80 TAS1R3 (0.53) POLBRAB9AL3MBTL1CHRM4PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed