Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284572 | 0.94 | TDO2 (0.54) | MAPTTDO2KDRTRPV1RAB9A | |
| SCHEMBL4701462 | 0.94 | MAPT (0.52) | MAPTTDO2KDRTRPV1RAB9A | |
| SCHEMBL14284599 | 0.93 | MAPT (0.51) | MAPTTDO2KDREGLN1TRPV1 | |
| SCHEMBL14284603 | 0.89 | MAPT (0.50) | MAPTTDO2KDRNPC1RAB9A | |
| SCHEMBL14284608 | 0.89 | TDO2 (0.50) | MAPTTDO2KDRTRPV1RAF1 | |
| SCHEMBL14284566 | 0.89 | TDO2 (0.50) | MAPTTDO2KDRTRPV1PTGS1 | |
| SCHEMBL14284604 | 0.89 | EPHX2 (0.55) | MAPTTDO2KDRNPC1RAB9A | |
| SCHEMBL5583578 | 0.89 | SMN1; SMN2 (0.53) | MAPTKDRTRPV1NPC1RAB9A | |
| SCHEMBL14284607 | 0.88 | MAPT (0.55) | MAPTTDO2KDRNPC1RAB9A | |
| SCHEMBL14284606 | 0.87 | MAPT (0.57) | MAPTTDO2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |