Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583850 | 0.94 | KDR (0.50) | SMN1; SMN2MAPTTP53NR1I2DHODH | |
| SCHEMBL5583752 | 0.89 | MAPT (0.57) | MAPTKDRTRPV1NPC1RAB9A | |
| SCHEMBL5584058 | 0.89 | NR1I2 (0.50) | SMN1; SMN2MAPTTP53NR1I2KDR | |
| SCHEMBL5583713 | 0.86 | KDR (0.46) | SMN1; SMN2MAPTTP53NR1I2KDR | |
| SCHEMBL5583684 | 0.85 | KDM4E (0.55) | SMN1; SMN2MAPTKDRLMNANPC1 | |
| SCHEMBL5583759 | 0.85 | KDR (0.47) | SMN1; SMN2MAPTTP53NR1I2KDR | |
| SCHEMBL5583595 | 0.85 | KLKB1 (0.48) | SMN1; SMN2MAPTTP53KDRNR1H4 | |
| SCHEMBL5583672 | 0.84 | SCN9A (0.54) | SMN1; SMN2MAPTKDRHDAC8HDAC6 | |
| SCHEMBL5583581 | 0.84 | KDR (0.49) | SMN1; SMN2MAPTKDRNPC1RAB9A | |
| SCHEMBL5583719 | 0.84 | NPC1 (0.53) | SMN1; SMN2MAPTKDRLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |