SCHEMBL5583770

SCHEMBL5583770

COc1ccnc(C(=O)Nc2cccc(Oc3ccccc3)c2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.52
RAB9A P51151 3/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPC1 O15118 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
NLRP3 Q96P20 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
KDM4E B2RXH2 2/20 0.49
PDGFRA P16234 2/20 0.48
POLB P06746 1/20 0.48
PGR P06401 1/20 0.48
KCNK3 O14649 1/20 0.48
KCNK9 Q9NPC2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14284587 0.94 PDGFRA (0.53) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL17706510 0.93 AR (0.51) GRM4RAB9AMAPTKMT2ANPC1
SCHEMBL14284584 0.93 GRM4 (0.52) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL14284596 0.93 GRM4 (0.55) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL14284570 0.92 PDGFRA (0.48) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL14284598 0.91 PNLIP (0.52) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL14284571 0.91 KCNK3 (0.49) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL14284574 0.90 GRM4 (0.49) GRM4RAB9AMAPTMEN1KMT2A
SCHEMBL2237038 0.90 RAB9A (0.53) RAB9AMAPTMEN1KMT2ANPC1
SCHEMBL14284591 0.89 KDM4E (0.52) GRM4RAB9AMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed