Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 7/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583615 | 0.88 | SMN1; SMN2 (0.55) | MAPTKDRPDGFRARAB9ASMN1; SMN2 | |
| SCHEMBL5583640 | 0.87 | SMN1; SMN2 (0.51) | MAPTMAPK1KDRPDGFRARAB9A | |
| SCHEMBL5583717 | 0.83 | KDR (0.48) | MAPTMAPK1RAF1KDRPDGFRA | |
| SCHEMBL5583670 | 0.81 | KDR (0.55) | MAPK1KDRPDGFRARAB9ASMN1; SMN2 | |
| SCHEMBL14284570 | 0.80 | PDGFRA (0.48) | MAPTRAF1KDRPDGFRARAB9A | |
| SCHEMBL5583728 | 0.79 | KMT2A (0.56) | MAPTKDRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14284569 | 0.79 | RAB9A (0.49) | KDRPDGFRARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14284583 | 0.79 | RAF1 (0.45) | MAPTMAPK1RAF1KDRBRAF | |
| SCHEMBL14284582 | 0.79 | MAPT (0.48) | MAPTMAPK1RAF1KDRSMN1; SMN2 | |
| SCHEMBL14284627 | 0.78 | RAF1 (0.49) | MAPK1RAF1KDRPDGFRABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |