Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.48 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 4/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583587 | 0.92 | KDR (0.48) | KDRSTK39PARGAXLSCN10A | |
| SCHEMBL5583625 | 0.91 | STK39 (0.57) | KDRPDGFRASTK39PARGAXL | |
| SCHEMBL5583779 | 0.87 | KDR (0.52) | KDRPDGFRASTK39MAPK9PARG | |
| SCHEMBL5584061 | 0.85 | PARG (0.60) | KDRPDGFRASTK39MAPK9PARG | |
| SCHEMBL5583670 | 0.84 | KDR (0.55) | KDRPDGFRAMAPK9AXLMAPK1 | |
| SCHEMBL5583786 | 0.83 | MAPT (0.45) | KDRPDGFRAMAPK9MAPTMAPK1 | |
| SCHEMBL5583823 | 0.82 | PGR (0.55) | KDRPDGFRASTK39MAPK9PARG | |
| SCHEMBL14284570 | 0.81 | PDGFRA (0.48) | KDRPDGFRAMAPK9MAPTRAF1 | |
| SCHEMBL5583684 | 0.81 | KDM4E (0.55) | KDRPDGFRAMAPK9MAPTKDM4E | |
| SCHEMBL4701462 | 0.81 | MAPT (0.52) | KDRMAPTBRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |