Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496294 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL11668838 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL7106488 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL9257620 | 1.00 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL23650045 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL1296681 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL11878700 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL1296828 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL731433 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 | |
| SCHEMBL9262129 | 0.98 | LPAR3 (0.57) | LPAR3LPAR2LPAR1CYP3A4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070045189-A1 | Acid mine water demineralization methods | GENERAL ELECTRIC COMPANY (US) | 2007-03-01 | — | — | US | disclosed |