Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210638 | 0.94 | KMT2A (0.38) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL2732942 | 0.80 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTMEN1KDM4E | |
| SCHEMBL8280226 | 0.77 | GRIA1 (0.39) | KMT2AALDH1A1MAPTLMNAGAA | |
| SCHEMBL25985564 | 0.69 | NPSR1 (0.48) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL9585593 | 0.68 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1NPSR1HPGD | |
| SCHEMBL31226129 | 0.66 | ALDH1A1 (0.45) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL31226160 | 0.66 | NPSR1 (0.45) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL22609347 | 0.66 | NPSR1 (0.45) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL5431807 | 0.66 | NPSR1 (0.45) | KMT2AALDH1A1MAPTMEN1NPSR1 | |
| SCHEMBL19893057 | 0.66 | NPSR1 (0.45) | KMT2AALDH1A1MAPTMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
| US-20050245518-A1 | Antiproliferative agents | METHYLGENE, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245518-A1 | Antiproliferative agents | HDAC1, HDAC11, HDAC5 | KMT2A 123/4885ALDH1A1 758/4885MAPT 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.