SCHEMBL22609347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL436752	0.81	ALDH1A1 (0.48)	ALDH1A1
	SCHEMBL25985564	0.80	NPSR1 (0.48)	NPSR1KMT2AALDH1A1MAPTMEN1
	SCHEMBL9585593	0.78	ALDH1A1 (0.50)	NPSR1KMT2AALDH1A1MEN1USP2
	SCHEMBL22609288	0.78	GRIA1 (0.46)	KMT2AALDH1A1MEN1GPX4
	SCHEMBL15248892	0.78	BRD4 (0.41)	KMT2AALDH1A1ALOX15HSD17B10POLB
	SCHEMBL31226160	0.77	NPSR1 (0.45)	NPSR1KMT2AALDH1A1MAPTMEN1
	SCHEMBL19893057	0.77	NPSR1 (0.45)	NPSR1KMT2AALDH1A1MAPTMEN1
	SCHEMBL31226129	0.77	ALDH1A1 (0.45)	NPSR1KMT2AALDH1A1MAPTMEN1
	SCHEMBL5431807	0.77	NPSR1 (0.45)	NPSR1KMT2AALDH1A1MAPTMEN1
	SCHEMBL4777369	0.76	ALDH1A1 (0.51)	NPSR1KMT2AALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.