Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359549 | 0.92 | CYP3A4 (0.37) | PPM1BPTPN1PPP1CCTP53CA12 | |
| SCHEMBL5608543 | 0.90 | SMN1; SMN2 (0.39) | PPM1BPTPN1PPP1CCTP53CA12 | |
| SCHEMBL6454360 | 0.84 | PPM1B (0.39) | PPM1BPTPN1PPP1CCCA12CA1 | |
| SCHEMBL1861830 | 0.74 | PPM1B (0.37) | PPM1BPTPN1PPP1CCCA12CA1 | |
| SCHEMBL8601101 | 0.73 | PPM1B (0.41) | PPM1BPTPN1PPP1CCCA12CA1 | |
| SCHEMBL9541118 | 0.73 | PPM1B (0.41) | PPM1BPTPN1PPP1CCCA12CA1 | |
| SCHEMBL10600065 | 0.73 | PPM1B (0.41) | PPM1BPTPN1PPP1CCCA12CA1 | |
| SCHEMBL5584855 | 0.72 | — | — | |
| SCHEMBL8555632 | 0.72 | — | — | |
| SCHEMBL5608583 | 0.71 | ALDH1A1 (0.33) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7164047-B2 | Subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis in the presence of a base, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, and reducing the obtained cyclopropylacetaldehyde; low cost, industrially advantageous | KURARAY CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20050020846-A1 | Subjecting a 3-cyclopropyl-2,3-epoxypropionic acid ester to solvolysis in the presence of a base, treating the product of the solvolysis with an acid to obtain cyclopropylacetaldehyde, and reducing the obtained cyclopropylacetaldehyde; low cost, industrially advantageous | KURARAY CO., LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1445248-A1 | PROCESSES FOR PREPARATION OF CYCLOPROPYLETHANOL, CYCLO-PROPYLACETONITRILE AND INTERMEDIATES OF BOTH | KURARAY CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |